Acarbose has a significant effect in male mice and a small but significant effect in female mice, possibly due to males being more sensitive to high glucose levels.

“did those animals both the treatment and the control groups weigh the same no a carbos led to weight loss or a lack of weight gain we don't understand it we see that in some populations but not all in the original itp paper the a carbos streeted mice were lower in weight than the control mice but then my own lab made a whole batch of a carbos treated mice for another purpose and we didn't see a dramatic change in weight and we really don't know why so it's a little bit frustrating and a little bit mysterious and embarrassing we don't always see the same weight change”

“no a carbos led to weight loss or a lack of weight gain we don't understand it we see that in some populations but not all in the original itp paper the a carbostreeted mice were lower in weight than the control mice but then my own lab made a whole batch of a carbos treated mice for another purpose and we didn't see a dramatic change in weight and we really don't know why”

“why the acaros has such a big effect in males and a small significant but small effect in females is unknown it presumably has to do with males being more sensitive to high glucose levels a carbos probably works by limiting very high glucose levels maybe for unknown reasons that triggers something horrible in the males and not so much in females”

“why the acaros has such a big effect in males and a small significant but small effect in females is unknown it presumably has to do with males being more sensitive to high glucose levels a carbos probably works by limiting very high glucose levels maybe for unknown reasons that triggers something horrible in the males and not so much in females”