Paul Saladino· MD
if you have one copy your risk is increased maybe two to three times particularly in Caucasians and Asians not so much or at all in Hispanics and african-americans or people of African Orange in African descent
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
if you have one copy your risk is increased maybe two to three times particularly in Caucasians and Asians not so much or at all in Hispanics and african-americans or people of African Orange in African descent
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all things equal from a clinical perspective we are more worried when someone of asian or caucasian ethnicity has it versus someone of latin or african descent
the hispanic latino latinx population carrying an e4 does not produce the same risk of a.d compared to white people or japanese people carrying the 8.4