Rhonda Patrick· PhD
So these have often been called cortical presentations, which have been noted for years by people like Professor Mario Mendez, to be typical in younger presentations of Alzheimer's and often in ApoE4 negative individuals.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So these have often been called cortical presentations, which have been noted for years by people like Professor Mario Mendez, to be typical in younger presentations of Alzheimer's and often in ApoE4 negative individuals.
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So they tend to be young, and we see them in their late 40s, mid 50s very commonly. We've seen them as late as starting their first symptoms in the mid-60s, but typically, their first symptoms are currying in the 40s and 50s. They are often women, they are often ApoE4 negative although not always.