Paul Saladino· MD
there's some data to indicate that ketones can suppress oxidative stress and also suppress the the complex that when it's activated sets off an inflammatory cascade of cytokines and in various model systems this is the endogenous metabolite ketones have been very a powerful regulator of histone deacetylase inhibitors which activate antioxidant systems and also they can suppress the nlrp3 inflammasome which when activated sets off an inflammatory cascade that is a root cause of many many age-related chronic diseases autoimmune diseases radiation injury in the brain you have the activation of this complex causing neuro inflammation