Peter Attia· MD
now think about it if it goes down it's not going down because they're apoe status changed and it's not going down because their age got younger it can only go down because the ratio of ab 42 to ab40 changed so what we're basically saying is we do have a biomarker that measures the change in you know amyloid 42 to 40 and potentially Tau eventually and is that predictive of an improvement I don't know the answer