The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Now, that process happens in Parkinson's disease as well with a different protein, alpha-synuclein. But actually, we believe it's happening to thousands of proteins. And a few years ago, we published a paper where we showed that many hundreds, if not thousands of proteins, undergo conformational change during aging and come out of solution.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And I think this is really important because here's a process that's been studied for decades in the context of neurological disease, Alzheimer's and Parkinson's and so on. But if the same process is happening in the course of normal aging, it shows a connection between normal aging and disease and that's something I think that lots of us are interested in right now.