Type 1, Type 2, and Type 1.5 Alzheimer's presentations are typically amnestic and more common with ApoE4, while Type 3 often presents with non-amnestic symptoms.

“Now there are some overlaps, the type 1s and the type 2s are typically amnestic presentations more common with ApoE4, and that's true for the type 1.5s as well. The type 3s, the toxic ones are quite different. They often present with a non-amnestic presentation. It's executive dysfunction, problems with calculation, problems with visual perception, problems with word finding, so-called primary progressive aphasia, all of these things, they are really bi-parietal presentations as opposed to bi-temporal presentations, essentially.”