Paul Saladino· MD
the failure or the re-imagining of a paradigm for dementia which cannot be based on drug targets for amyloid plaques or Tau fibrillary Tangles as far as we know now
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We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
the failure or the re-imagining of a paradigm for dementia which cannot be based on drug targets for amyloid plaques or Tau fibrillary Tangles as far as we know now
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
and especially on the heels of really I would say the failure or the re-imagining of a paradigm for dementia which cannot be based on drug targets for amyloid plaques or Tau fibrillary Tangles as far as we know now