The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
what we are learning now is that a pro ii for or at least alzheimer's is also probably linked to insulin resistance and i think when people here in this situation is I can't eat high fat and they moderate or high carbohydrate and you're thinking ah this is all speculative right I'm just not convinced this is the problem
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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those who look to be more insulin resistant in a standard American diet context
the data is less concerning for those who are insulin sensitive and there is a connection between insulin resistance and increased incidence of dementia in those with apoe4
if you look at the research in people who are insulin resistant it looks like apoe4 heterozygosity or homozygosity having an apov4 allele could lead to a higher preponderance of problems with dementia
But I firmly believe that if you can be as insulin-sensitive as possible, for you as an individual you reduce your risk.