A diet very low in carbohydrates and saturated fat would likely lower ApoB, but potentially not to levels that make cardiovascular disease irrelevant for most people.

“so if you were on a really low carbohydrate really low saturated fat diet you would indeed lower your APO B would you lower it to the levels that I think are necessary to make ascvd irrelevant most people probably not um and then would that be a diet that for most people is sustainable long term you know that's probably a very individual decision”