Peter Attia· MD
You have to instead look at cortisol metabolites like tetrahydrocortisol, tetrahydrocortisone to truly measure that.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
You have to instead look at cortisol metabolites like tetrahydrocortisol, tetrahydrocortisone to truly measure that.
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the sum total of these is how I learn what the total adrenal output is
you do need to have some sense of what their metabolites are because that's what's actually telling you total adrenal output next thing you need to understand is the balance of cortisol and cortisone
The reason we like the Dutch test is first of all it is measuring free cortisol secondly it's measuring cortisol metabolites and cortisol metabolites are very helpful when it comes to understanding what cortisol production looks like