Many individuals diagnosed with adrenal fatigue or hypercortisolism may have been misdiagnosed due to the limitations of testing methods like blood-based cortisol evaluations compared to dried urine tests.

“the take home here is very difficult if not impossible to impute what's going on with adrenal function by looking at a blood test because it's looking at total cortisol and if that weren't bad enough it's just one snapshot in time you really do need to see what's going on in total secondly took free cortisol and free cortisone by themselves still don't tell you a total picture you do need to have some sense of what their metabolites are because that's what's actually telling you total adrenal output”

“the take home here is very difficult if not impossible to impute what's going on with adrenal function by looking at a blood test because it's looking at total cortisol and if that weren't bad enough it's just one snapshot in time you really do need to see what's going on in total secondly took free cortisol and free cortisone by themselves still don't tell you a total picture you do need to have some sense of what their metabolites are because that's what's actually telling you total adrenal output”