Paul Saladino· MD
people that are a little more muscular have more creatine in the muscle and may have a slightly higher creatinine concentration in the blood
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
people that are a little more muscular have more creatine in the muscle and may have a slightly higher creatinine concentration in the blood
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creatinine is an imperfect measure of kidney function it is a breakdown of creatine from the muscles it's not actually a direct indicator of kidney function it is an indicator of molecule that results from the breakdown of creatine in the muscles and is thought to be a good metric or proxy for kidney function but it's not perfect