it is therefore my belief that the more we can do to screen for cancer and catch it earlier the better we will be
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
it is therefore my belief that the more we can do to screen for cancer and catch it earlier the better we will be
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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early detection absolutely matters and you have to look no further than that simple point which hasn't i've never seen it refuted less tumor burden it's less heterogeneity equals better outcomes it's an axiom that's correct it's absolutely true
simply is no ambiguity that the earlier you catch cancer the better your odds are at treating it while it remains local
this is what we're talking about is behind this you know massive like wave of enthusiasm um and it's it's um legitimate enthusiasm not hype that early detection is going to allow our same toolbox of drugs to be massively more effective
the sooner we know we have cancer and the sooner we can begin treatment the better we are
my bias is that early detection leads to earlier treatment and even if the treatments are identical to those that will be used in advanced cancers the outcomes are better because of the lower rate of tumor burden
step number two is if you do get cancer you want to be able to catch it as soon as possible so that you have the smallest possible burden of this disease to treat
Whole-body MRI screening in healthy adults produces more incidentaloma harm than cancer-mortality benefit.
Starting colonoscopy screening at 45 (vs 50) prevents enough early-onset cancers to justify the population cost.
Multi-cancer liquid-biopsy tests like Galleri detect early cancers at a stage that meaningfully improves survival.