The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
a lot a common feature of cancer cells is that they behave um like their sort of progenitors or precursors like in development right all mature cells in the body come from a you know well a stem cell of you know of a of some sort — and there's lineage in different different lineages and different types of stem cells But ultimately you see cancers actually adopt sort of a biological Behavior that's like backing up if you will in the developmental um process
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
and it turns out that developmental cells um have surface um you know proteins uh surface you know markers if you will that are not expressed in in fully mature tissues and the immune system can see those
we we began to understand some time ago that a lot a common feature of cancer cells is that they behave um like their sort of progenitors or precursors like in development right all mature cells in the body come from a you know a stem cell of you know of a of some sort um and there's lineage in different different lineages and different types of stem cells But ultimately you see cancers actually adopt sort of a biological Behavior that's like backing up if you will in the developmental um process this is part of the just a consequence of the genetic alterations or the combination lock is I often refer to it of genetic alterations that can lead to cancer is that that's one of the programs that they typically adopt and it turns out that developmental cells have surface um you know proteins surface you know markers if you will that are not expressed in in fully mature tissues and the immune system can see those
Whole-body MRI screening in healthy adults produces more incidentaloma harm than cancer-mortality benefit.
Starting colonoscopy screening at 45 (vs 50) prevents enough early-onset cancers to justify the population cost.
Multi-cancer liquid-biopsy tests like Galleri detect early cancers at a stage that meaningfully improves survival.