Peter Attia· MD
There's an additional complication, or not complication, but intervention that is also important, which is once you start doing glycolysis at a higher rate, the process of doing glycolysis incorporates an inorganic phosphate to make a doubly phosphorylated and 1,6-bisphosphate. And so that additional consumption of inorganic phosphate drops a negative regulator of inosine deaminase, and that drops the ability to keep ATP synthesis going on in the cell. So the combination two drops the ATP level dramatically. And now the glucose that's coming in is flooding through glycolysis, but it's going into all these anabolic processes. It's being used to make lipids. We see all the label from glucose going into fatty acid synthesis and serine synthesis and nucleotide synthesis going up five or tenfold. It's really quite dramatic what happens.