stem cell replication rates do vary between different organs and this can be correlated to a higher incidence of cancer for that particular organ for example in humans colon cancer is much more common than cancer of the dun dadum the first part of the small intestine stem cells in the colon divide divide 10 the 12 times whereas stem cells in the duodenum divide 10 to the 10 times so stem cells are dividing much more rapidly over a lifetime in the colon versus the duodenum