because they over produce oxygen free radicals in the context of high oxygen you can push the cells above their antioxidant potential and then trigger apoptosis so it's like a double-edge so it's a it's basically a u-shaped curve or inverted depending on how you want to think about it where exactly cancer cell is not only after by survivor it's optimized to thrive at a certain level of elevated reactive oxygen an elevated level but if you go too far it becomes counter