Acquired mutations in cells can produce proteins or molecules recognized by the immune system.

“these mutations these changes in DNA that are random events as the cell is as the cell is dividing can produce proteins that can be recognized or other molecules recognized by the immune system and they do it in complex Ways by breaking down small Mo small peptides and putting it on the cell surface but the immune system can recognize these mutations and it's only been in the last I'd say three or four years that we now recognize these mutations uh as commonly recognized by by the immune system”