Avastin (bevacizumab) contributes to the invasive behavior of tumor cells and enhances hypoxic factors that benefit cancer.

“all it does is contribute to the invasive behavior of his tumor cells and all of these other things you're basically driving this idea which I haven't wrapped my head around yet is you're actually enhancing the promotion of the hypoxic factors that are giving cancer some of its selective benefit yeah and it's force and don't forget the cells that are invading which are coming from disrupted microglia in the brain macrophages they will invade they're already have the capacity to do this they live without blood vessels so so you're facilitating the invasive behavior”