The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
it might be less about the given histology and more so you know it's funny I talked to Keith Flaherty recently and this is a great example of targeted therapy and cancer right imagine you have your tumor you get it sequenced and you realize oh look you you have a tumor whose mitochondria are especially weak you are a great candidate for hyperbaric oxygen
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
hyperbaric oxygen has definitely been proposed as a cancer therapy in the past but there been mixed signals and exactly as you're saying it may be the case that if you know how to precisely target it maybe you'll see a real signal
our idea is the exact opposite maybe in certain instances you want to flood them with oxygen
the cancer front people have talked about hyperbaric oxygen being a very potent tool because the mitochondria of cancer cells are going to be defective on balance relative to the non cancer cells
Whole-body MRI screening in healthy adults produces more incidentaloma harm than cancer-mortality benefit.
Starting colonoscopy screening at 45 (vs 50) prevents enough early-onset cancers to justify the population cost.
Multi-cancer liquid-biopsy tests like Galleri detect early cancers at a stage that meaningfully improves survival.