I think that metabolic dysfunction plays a very important role in causing cancer. Most primarily through inflammation through all the effects of, like the insulin signaling and the inflammation, the reactive oxygen species. All these things that are damaging the cell, but I don't necessarily see it the way that you, sort of, described it as them... [Dom]: An initiator. [Rhonda]: Yeah, them changing or activating oncogenes. I don't think that's really been shown.