Adjuvant therapy with HER2 antibodies like trastuzumab can cure microscopic metastatic disease.

“So the adjuvant setting. So the possibility, but not certainty that microscopic metastatic disease exists. You give therapy in that situation, systemic therapy to seek and destroy microscopic deposits. That's so-called adjuvant therapy. So with that jargon stated, adjuvant use of HER2 antibody. This was the first example of this is why I'm giving it its due credit. Cures patients, cures patients. You don't cure patients in the overt metastatic setting with HER2 antibody therapy. Like that's unheard of.”