Individuals diagnosed with definite FH are treated from age six due to the high certainty of life risk in the third decade of life.

“we would be treating an individual as young as six years of age which means our certainty with which this person's life is at risk in as early as the third decade of their life I.E in their 20s we're so sure of that we would do something that honestly I think a lot of people who don't especially if you don't really understand the pathophysiology of lipid metabolism would think that's absolutely insane now I obviously share your view which is that's absolutely not insane that's the only way that person is going to go on to live a long life”