Atherosclerosis can be present in individuals as young as their 20s and 30s, characterized by oxidized ApoB-bearing particles within macrophages and thickened intima.

“here's a 26 year old male victim of a gunshot wound here's a 27 year old female who died in a motor vehicle accident here's a so-and-so and so and so and when you look at their coronary arteries you realize they already have atherosclerosis they already have oxidized Papo B bearing particles engulfed by macrophages and thickened intima and while they may not have calcification in their arteries yet or the types of plaque that would rupture within the ensuing weeks or days or months they nevertheless had atherosclerosis and they were in their 20s and in their 30s”