In the Look Ahead trial, the hazard ratio for death from cardiovascular events was 0.95 with a 95% confidence interval of 0.83 to 1.09, indicating no statistically significant effect (p-value 0.51).

“so at the time that it was stopped the hazard ratio was 0.95 so there was a suggestion of a five percent reduction in in in the risk of death from cardiovascular events so in the right direction but the 95 confidence interval or uncertainty interval if we're going to adopt that terminology was 0.83 to 1.09 so it crossed one and so you know the p-value is going to be greater than 0.05 in fact the p-value was 0.5 0.51 or something like that I mean it was basically complete chance there was absolutely no effect and again no point in continuing”