Paul Saladino· MD
if you look into the science on that too it's also extraordinarily narrow and like I think it's something in neighborhood between 5 and 10 nanometers itself and it's it's kind of like a zipper it has lots of different cross proteins to allow for transmigration and so forth now important to note though I can tell you when that Gap opens and it opens with inflammation it's actually the 101 book for when endothelial cells intentionally separate from each other and it's and it's so as to make it porous and allow for monocytes to differentiate into macras where they can then get into the subendothelial space and take care of whatever debris or pathogens or so on and so forth that are in there