Peter Attia· MD
Genetic data suggest that the cardiovascular protective effect of lower LDL and lower triglycerides are both mediated by a reduction in ApoB particle concentration.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Genetic data suggest that the cardiovascular protective effect of lower LDL and lower triglycerides are both mediated by a reduction in ApoB particle concentration.
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atherogenic lipoproteins within that category though the things that are also emerging is what contributes to the atherogenicity of an apob particle triglycerides has really taken center stage how they affect lipoprotein concentration and quality or functionality whatever adjective you want to ascribe to it