The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Now, this has been most typically and most repeatedly measured using a test called V2 max. You've heard me talk about this, of course, um, and it's become a very popular thing that people talk about. It's the maximum rate at which the body can utilize oxygen. tested of course during maximal efforts which require exercise. Um so this number is expressed in milliliters of oxygen per kilogram of body weight per minute.
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people will be pretty familiar with the um term cardiorespiratory Fitness it's sometimes used interchangeably with V2 Max or your maximal oxygen consumption it's kind of a very popular biomarker these days with you know like you said um and we'll talk about later correlating with longevity and so on so cardiio respiratory Fitness is sort of the exercise physiologist measure of aerobic fitness it's very popular um as an endurance performance marker or that's traditionally how it was thought of because you know having a high view2 Max is kind of standard among high level endurance athletes but essentially what it is is your body's ability to take in oxygen take in air from the environment distribute it to the rest of the body through your cardiovascular system get that oxygen into mitochondria and skeletal muscle and then utilize that oxygen for energy in the form of ATP