ApoC3 is a pro-inflammatory protein that enhances VLDL production, retards clearance, and interferes with lipoprotein lipase hydrolysis, increasing the half-life of triglyceride-rich lipoproteins.

“tape oc3 it's a pro-inflammatory protein it really enhances VLDL production in the liver but it just retards their clearance and it probably interferes with the hydrolysis induced by lipoprotein lipase so you're increasing half-life's of all triglyceride rich lipoproteins which let's see ETP exchange occur longer and what is CTP exchange doing bringing more cholesterol - your V LDL particles enhancing cholesterol enrichment they're those V alleles or losing triglycerides of up the other in cholesterol so these are all the pathologies that might go on if you have delayed clearance and c3 is going to delay to clearance through multiple reasons of these particles”