Single nucleotide polymorphisms (SNPs) that alter LDL cholesterol levels but do not involve lipid malabsorption or the LDL receptor itself are under-investigated.

“we were only able to find one that confirmed her disease but were able to find one that confirmed no heart disease with high levels of LDL but then there were 24 25 that were not investigated non lipid metabolism based snips that were just straight up not investigated which was great now let's see curious in a conspiratorial way but I will say it's it's a bit frustrating that they didn't pursue that that they seem to only want to look at snips that do two things that change the LDL levels and have that lipid malabsorption potential”