The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
the LDL molecule is a I believe it's a monol layer um it's a lipid monol layer with an apob b00 in the in the membrane and also in the membrane are things like of course CoQ10 Etc and this is a particle it's a particle that moves cholesterol and um and triglycerides around our body
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so it's this spherical thing call it 20 nanometers in diameter and it has a outer spherical structure that is made of lipid cholesterol phospholipid inside it has a core that consists of cholesterol ester so this is none this is like the cholesterol without its bulky side chain and the triglyceride and on the outside as I mentioned it has this one a p-- of lipoprotein called a po b100
and the reason you can use a PO B as a surrogate for that is that each LDL particle has and a PO B which is an ape a lipoprotein that wraps around the spherical lipoprotein it's a PO b100 specifically so by counting those since each LDL has one and only one a PO B you can quantify the number of LDL particles
We've defined an LDL particle as a collection of cholesterol little bit of triglycerides wrapped by one peptide called APO lipoprotein B