Brain lipoproteins are recognized by neurons via LDL receptors, LRP, or scavenger receptors, allowing cholesterol uptake.

“aha the brain has to have a lipoprotein system just like the periphery does now between astrocytes and neuren neurons is basically its brain interstial fluid sort of a loose connective tissue it's called the matome so if asites synthesize cholesterol they obviously have to package it inside of a brain lipoprotein secrete that lipoprotein which swims through the matome and goes over and guess what the neuron expresses LDL receptors LDL receptor related protein or something called the scavenger receptor all of which can bind to the type of lipoprotein that an asy produces”

“what is the other cell and it's asites in again in infancy and childhood and utero alod dendrites asites and neurons are making cholesterol let you know tomorrow once the neuron stops making it astrocytes are the soul maker of cholesterol that supplies the neurons”

“if asites synthesize cholesterol they obviously have to package it inside of a brain lipoprotein secrete that lipoprotein which swims through the matome and goes over and guess what the neuron expresses LDL receptors LDL receptor related protein or something called the scavenger receptor all of which can bind to the type of lipoprotein that an asite produces”

“aha the brain has to have a lipoprotein system just like the periphery does”

“so the brain lipoprotein are all apoe or they're all apoe plus apoa1 and you can have multiple copies of each of those on those particles so wow so now as long as they APO A1 by the way which can bind to an LDL receptor or the scavenger receptor same with the apoe the neuron can grab them and either internalize them or delipidated them and the neuron gets its cholesterol and the neuron's happy”