Paul Saladino· MD
So, I think atherosclerosis is one of the few things that like is inevitable. Everybody's going to probably develop a certain amount of it, but not everybody has to go on to actually have clinical events.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
So, I think atherosclerosis is one of the few things that like is inevitable. Everybody's going to probably develop a certain amount of it, but not everybody has to go on to actually have clinical events.
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we know from autopsy studies of military personnel who unfortunately get killed in their job that these young men many of them robust in great shape have subclinical atherosclerosis but none of them are dropping Deb of heart attacks while they're serving in the military with rare exception so it takes a long long time