A risk-reward analysis should be conducted before considering cholesterol-lowering interventions for healthy individuals with higher-than-ideal cholesterol.

“and then take that in consideration with all cause mortality factors and it actually makes it so that it's not really clear that just lowering cardiovascular disease with these drugs is necessarily a good idea and that is especially the case which was your point Paul and Derrick's podcast in someone who is healthy who is healthy by all means but just has a higher than ideal cholesterol value it's like oh well maybe it's maybe we should actually really consider this and lay out all the factors for this risk RIS reward profile like let's do our Benjamin Franklin list our Pros versus cons and weigh this”