Many individuals have compromised kidney function that is not apparent from creatinine levels alone and may not become clinically relevant for decades.

“there are a lot of people walking around I mean a staggering amount of people are walking around who on the surface just based on their creatinine look pretty normal but a slightly deeper look says no actually they're not normal they are they are compromised and it won't be clinically relevant for 30 or 40 years”