Paul Saladino· MD
Seed oils increase Lp(a) (PMIDs: 21466598, 14739118). Lp(a) is known to be pro-atherogenic, pro-thrombotic and pro-inflammatory (32453609)
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Seed oils increase Lp(a) (PMIDs: 21466598, 14739118). Lp(a) is known to be pro-atherogenic, pro-thrombotic and pro-inflammatory (32453609)
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
Seed oils increase Lp-PLA2 (Lipoprotein-associated phosholipase A2) (PMID: 28503188). Increased LP-PLA2 is strongly associated with increased cardiovascular disease (PMIDs: 22499993, 17431184)
controlled trials that show that seed oils do some really nasty things like increasing lipid peroxidation oxidized LDL LP little a and lppla2 I don't think any cardiologist on the planet would argue that if you're doing those things that that is going to lead to heart disease