The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
hdl2 and hdl3 which are the classic two main quote subclasses of HDL these are different sizes and different densities of HDL that again were isolated by centrifugation and by their flotation properties hdl2 is bigger hd03 is a little smaller hdl2 has mostly four molecules of apoa1 hdl3 has mostly three molecules of APO A1
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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the numbering of the APO lipoproteins or the apoa lipoproteins one two four five is totally independent of the numbering of the HDL particles