TMAO levels in humans correlate with heart disease risk and may contribute to heart disease by causing atherosclerosis.

“and in humans they showed that in there were two different papers the first one looked at choline and the second one looked at meat but what they were showing was that TMAO levels in humans corley with heart disease risk and when humans eat either choline or carnitine they will metabolize both of those two trimethylamine in the gut and the liver will convert it to TMAO and so the argument is the TMAO and those humans will cause heart disease the way that it causes heart disease in the genetically engineered mice”