Peter Attia· MD
all they know is that person has extra cholesterol in your small V LDL particles but vldls depending on two things it's a pony content and it's a possi three content is going to be virtually instantly cleared so if your V small V LDL particles are being rapidly cleared by your a Poli April be 100 receptors in other words if you took a bunch of small V LDLs and some of them have lots of a Bowie and very little a possi three those aren't remnants they're not pathological or Knights vldls that's what they are but are they disease-causing VOD le ah look some of them probably getting button vers le o particle number so and also read and very few relative to a small VLDL that would be high in a potato see the main down there's a lot of downsides tape oc3 it's a pro-inflammatory protein it really enhances VLDL production in the liver but it just retards their clearance and it probably interferes with the hydrolysis induced by lipoprotein lipase so you're increasing half-life's of all triglyceride rich lipoproteins which let's see ETP exchange occur longer and what is CTP exchange doing bringing more cholesterol - your V LDL particles enhancing cholesterol enrichment they're those V alleles or losing triglycerides of up the other in cholesterol so these are all the pathologies that might go on if you have delayed clearance and c3 is going to delay to clearance through multiple reasons of these particles