The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
the HDL which let's say it's this other marker here they have another a different marker called an APO A1 they can have from one to five of them on their structure and it's not very accurate to measure that because what if one has one and one has five they're mostly in the form of Threes but generally they can have up to five on each HDL
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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HDLS are really complicated and we don't even come close to understanding all the ins and outs of them
it also is a Core protein essentially of HDL but unlike April B there are several molecules of apoa1 On Any Given HDL particle we'll probably talk more about that but anywhere from one to four maybe in some cases a little bit more and also apeway1 doesn't stay with the particle it can exchange onto other types of mostly HDL particles but even sometimes onto ape will be containing like lipoproteins
what we've really learned in the last decade or so is that apoa1 is put into the blood by either the intestinal enterocyte or the hepatocyte in the liver as more or less a free protein so it's secreted as a protein one of the first steps that has to happen for HDL to be formed is that HDL once it comes out of the cell engages with a key transport protein called ABC A1 which its role abca1's role is to take lipid cholesterol and other types of lipids called phospholipids from the cell and Export them to the newly secreted apoa1