Promoting cholesterol efflux pathways via ABCA1 and other transporters, driven by apoA1 to HDL, protects against early atherosclerotic plaque initiation and progression.

“that one of the best ways to get rid of it would be to promote these efflux Pathways via abca1 and other transporters that are being driven by apoa1 to HDL which then by my garbage truck analogy the garbage truck the I.E the HDL is picking it up in the periphery like the blood vessel and returning it to the liver dumping it off in the liver and then going back and doing its job again this process of quote efflux cholesterol efflux from macrophages and frankly other cells particularly in the blood vessel wall has been for a long time now thought of as a key process that would help to protect against the early initiation and progression of the atherosclerotic plaque”