The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
i can measure apo b or non-hdl cholesterol with much less error than i can measure your risk the variables that we know michael pincinis calculated we were account for about 20 percent of the variance in risk okay that's about it that's not such a that's not such a large number that's a it's a small number
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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the measurement of hdl cholesterol is not standardized the measurement of ldl cholesterol not standardized the measurement of triglycerides not standardized well the other argument in terms of the cost argument because i actually had that argument with a physician as recently as three months ago who accused me of getting apob on patients as a way to up charge them even though i don't make any money on labs but i actually called the lab that we use and said what's your cash price for apob you want to know what it was please two dollars and fifty cents right that's a real it's a real money maker yeah yeah you know how much it is in my hospital it's two dollars okay it the the the there's a there's a i'm trying to say this moderately this cost argument has been used without documentation as a as a killer argument and and there were labs that charged way too much welcome to america okay uh you're in general your your charges are higher than ours in my little country but that's a function of how much somebody's billing not a function of what the assay costs and and apob it really ticks me off because if you take india for a moment or or almost anywhere if a doctor gets a report now he gets total cholesterol triglycerides non-hdlc ldlc hdlc five numbers do you think he actually looks at any of those numbers if he try he's trying to do a good job he does but let's say the triglycerides are high can he do anything with that nope because everything is based