Low HDL cholesterol concentration is often associated with hypertriglyceridemia and has a greater impact on the atherogenic index than raised LDL cholesterol for predicting ischemic heart disease events.

“they found a low hdl cholesterol concentration is not often observed as an isolated disorder but also includes hypertriglyceridemia in addition a reduced plasma hdl was found to have a greater impact than raised ldl cholesterol on the atherogenic index this ratio being the best variable of the traditional lipid profile for the prediction of ischemic heart disease events in the quebec cardiovascular study”