Peter Attia· MD
in that case you're impacting a cell's capability of uptake for lipids or flipper proteins right yes you are in that situation those patients livers will take up less LDL because they pcsk9 is a protein that does among other things degrades the LDL receptors because they have hyper functioning pcsk9 they are more rapidly degrading their LDL receptors on the livers so they're taking up less LDL particles