Two large clinical trials showed minimal effects of niacin on reducing cardiovascular events.

“well the clinical trials you know got done the high trial which was a very well done trial which frankly just didn't show much benefit of niacin a blow to us but the field comes up with reasons why that trial may not have been right bottom line is one more trial run by Merck with a drug that also helped to potentially address some of the issues with niacin was done a very large trial very well-powered trial and that also had really minimal or very disappointing effects on reducing cardiovascular events essentially those two trials killed niacin”