Peter Attia· MD
the women are very rarely smoking they also almost never have diabetes so they're thin active women have high hdls and don't smoke
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
the women are very rarely smoking they also almost never have diabetes so they're thin active women have high hdls and don't smoke
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there are some explanations very frequently those women have very high HDL cholesterol so perhaps some people have such an efficient reverse cholesterol transport system that they can take care of the deposited LDL in the macrophage on the tendons everywhere it's almost like the reverse cholesterol transport back to the liver is so fast that you can dump anything on them doesn't matter
remember the woman I'm describing is a nice thin elderly grandmother who's very active jumping up and down doesn't smoke and her High HDL is definitely not a sign of something dysfunctional