Primary hemostasis involves a platelet plug for minor vascular breaches, while secondary hemostasis involves fibrin for larger injuries.

“primary hemostasis you only need a platelet plug there's some hole in in the vasculature and a platelet plug does the job and you're fine that's that happens constantly and all the time in your vascular secondary hemostasis is there's something bigger it's a little more complex so the immune response is to try to with fibron capture it trap trap it try that's where plotting becomes helpful”