Paul Saladino· MD
that was of course by Design like getting back to the context in aspect right the we needed to pass an IRB you can't you can't go to an IRB and say we want to we want to allow people to not have therapy who have existing cardiovascular disease for example right that's that's a no-brainer um but that's okay because that was the whole point was we wanted to get people who are healthy with extremely high levels of LDL and then capture how much direct like I think it really I'm going to really draw out that point that I was making earlier because I think a lot of people miss this when I'm trying to bring it to everyone's attention