Genetic variations in Lp(a) isoform sizes contribute to differences in Lp(a) levels among individuals.

“part of the genetic heterogeneity among different people is the the apo lipoprotein a isoform size so people express different lpa isoforms some some are bigger than uh than the other and that that probably uh that well that actually plays an important part of the uh equation explaining why some people have a higher lp a little late than others”

“so you're going to see different expressions of the apo lipo protein little a this apo lipoprotein little a which we'll talk a lot about and what it looks like and its structure and what its heterogeneity is all about”